The Reaction ofN-Substituted Carbonimidic Dihalides with Grignard Reagents. The Generation of Alkyl or Aryl Halides from Grignard Reagents
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چکیده
منابع مشابه
Iron nanoparticles in the coupling of alkyl halides with aryl Grignard reagents.
Iron nanoparticles, either formed in situ stabilized by 1,6-bis(diphenylphosphino)hexane or polyethylene glycol (PEG), or preformed stabilized by PEG, are excellent catalysts for the cross-coupling of aryl Grignard reagents with primary and secondary alkyl halides bearing beta-hydrogens and they also prove effective in a tandem cyclization/cross-coupling reaction.
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The use of transition-metal catalysis to form new C C bonds is an important tool in organic synthesis. Palladiumand nickel-catalyzed C C bond-forming reactions have been extensively explored and are well understood. The use of iron as the catalyst has gained much less attention, despite the innovative work of Kochi et al. in the 1970s. Recently, several groups have turned their attention toward...
متن کاملSingle electron transfer-induced cross-coupling reaction of alkenyl halides with aryl Grignard reagents.
Alkenyl halides were found to undergo coupling with aryl Grignard reagents to give the corresponding styrene derivatives in a stereo-retained manner. The cross-coupling reaction is considered to proceed through a single electron transfer mechanism.
متن کاملIron(III) amine-bis(phenolate) complexes as catalysts for the coupling of alkyl halides with aryl Grignard reagents.
Catalytic cross-coupling of aryl Grignard reagents with primary and secondary alkyl halides bearing beta-hydrogens is achieved using Fe(III) amine-bis(phenolate) halide complexes.
متن کاملCopper nanoparticle-catalyzed cross-coupling of alkyl halides with Grignard reagents.
A cross-coupling reaction between alkyl bromides and chlorides and various Grignard reagents was carried out in the presence of commercially available copper or copper oxide nanoparticles as a catalyst and an alkyne additive. The catalytic system shows high activity, a broad scope, and good functional group tolerance.
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1975
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.48.1862